April 2, 2022
East St. Louis - East St. Louis, IL
Girls' 4 x 800 Relay
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| PL | TEAM | ATHLETES | TIME | TIME | TIME | TIME | SC |
|---|---|---|---|---|---|---|---|
| 1 | Belleville East | Devynisha Deere, Bria Johnson, Brenae Falls, Tawney Anaya | 12:19.37 | 11:18.32 | 13:00.07 | 11:18.32 | 10 |
| 2 | East St. Louis | Di Najhia Griggs, Le'Nikei Burns, Brenay Smith, Zhakeya Hawkins | 11:33.17 | 12:09.65 | 9:51.02 | 14:35.58 | 8 |
| 3 | Hazelwood Central | Devyn Shelton, Aliya Catching, Skye Maxwell, Marsae Elam | 12:04.27 | 12:11.58 | 13:02.79 | 12:55.48 | 6 |
| 4 | Hazelwood East | Jocelyn Archie, Nevaeh Mosby, Chloe Rainey, Kendall Strong | 12:43.04 | 12:13.69 | 12:50.38 | 11:07.66 | 5 |
| 5 | Southeast (Springfield) | Melodi Victory, Jasiah Singleton, Mia Hinkle, Kairy Mercado | 11:43.93 | 12:53.54 | 13:09.01 | 10:57.51 | 4 |
| Lanphier | Ashley Watson, Sophie Lewis, Julia Longstaff, Mykail Brown | DNS | DNS | DNS | DNS |